Guidance

Annexe B: Changes to the selective neonatal Hepatitis B immunisation pathway for babies born to Hepatitis B infected mothers

Published 30 April 2025

Age Vaccine Change
At birth Monovalent hepatitis B (Engerix B/ HBvaxPRO) None
4 weeks Monovalent hepatitis B (Engerix B/ HBvaxPRO) None
1 year   Remove monovalent Hepatitis B (Engerix B/HBvaxPRO) vaccine dose (note 1)

Blood test (usually performed as a dried blood test) for HepB surface antigen to be completed between one year and 18 months of age

Note 1: This final HepB dose will be provided by the additional routine Hexavalent dose (4th dose of DTaP/IPV/Hib/HepB) offered at 18 months.